Preparation and retention mechanism exploration of mesostructured cellular foam silica as stationary phase for high performance liquid chromatography
详细信息 查看全文
- 作者：Shaoai Sun ; Xiaoqiong Zhang ; Qiang Han ; Wei Wan ; Mingyu Ding ; dingmy@mail.tsinghua.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mesostructured cellular foam ; Stationary phase ; High performance liquid chromatography ; Retention mechanism ; Proteins
- 刊名：Talanta
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：149
- 期：Complete
- 页码：187-193
- 全文大小：1311 K
文摘
- •
HPLC packing materials with interconnected porous structure and ultralarge pore size were synthesized.
- •
Pore diameter could be well tailored.
- •
Effective separation of proteins and small molecules was achieved.
- •
A mixed-mode retention mechanism of the prepared stationary phases was proposed.
- •
Molecular sieving effect played an important role in protein separation on our home-made HPLC column.