Chemical constituents of fine particulate air pollution and pulmonary function in healthy adults: The Healthy Volunteer Natural Relocation study

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• 作者：Shaowei Wu ; Furong Deng ; Yu Hao ; Masayuki Shima ; Xin Wang ; Chanjuan Zheng ; Hongying Wei ; Haibo Lv ; Xiuling Lu ; Jing Huang ; Yu Qin ; Xinbiao Guo
• 关键词：Al ; aluminum ; As ; arsenic ; Ba ; barium ; BIT ; Beijing Institute of Technology ; BMI ; body mass index ; Ca ; calcium ; Cd ; cadmium ; Cl&minus ; chloride ; CI ; confidence interval ; CO ; carbon monoxide ; Co ; cobalt ; Cr ; chromium ; Cu ; copper ; EC ; elemental carbon ; F&m
• 刊名：Journal of Hazardous Materials
• 出版年：2013
• 出版时间：15 September, 2013
• 年：2013
• 卷：260
• 期：Complete
• 页码：183-191
• 全文大小：1159 K

文摘

The study examined the associations of 32 chemical constituents of particulate matter with an aerodynamic diameter ¡Ü2.5 ¦Ìm (PM_2.5) with pulmonary function in a panel of 21 college students. Study subjects relocated from a suburban area to an urban area with changing ambient air pollution levels and contents in Beijing, China, and provided daily morning/evening peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV₁) measurements over 6 months in three study periods. There were significant reductions in evening PEF and morning/evening FEV₁ associated with various air pollutants and PM_2.5 constituents. Four PM_2.5 constituents (copper, cadmium, arsenic and stannum) were found to be most consistently associated with the reductions in these pulmonary function measures. These findings provide clues for the respiratory effects of specific particulate chemical constituents in the context of urban air pollution.