Wheat straw (WS) was pretreated to get variability in chemical composition.
Cellulolytic enzymes were produced by using chemically and structurally different WS.
Amorphous pretreated wheat straw/cellulose gave higher cellulase production.
Enzyme produced by using untreated WS gave better pretreated wheat straw hydrolysis.
Untreated wheat straw is a good carbon source for diverse cellulase secretion.