Polymer based microspheres of aceclofenac as sustained release parenterals for prolonged anti-inflammatory effect

详细信息    查看全文

• 作者：Manpreet Kaur ; Sumit Sharma ; VR Sinha ; ^{sinha_vr@rediffmail.com}
• 关键词：Microspheres ; Aceclofenac ; PLGA ; PCL ; Parenterals ; Anti-inflammatory
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：72
• 期：Complete
• 页码：492-500
• 全文大小：1066 K
• 卷排序：72

文摘

PLGA and PCL polymeric microspheres for parenteral prolonged drug delivery system were formulated. Polymeric microspheres were characterized physically and drug excipient incompatability. Three months accelerated stability studies were carried for drug loaded polymeric microspheres. Pharmacodynamic studies prove the rationality of sustained therapeutic effect of designed drug delivery system.