Activity of fosfomycin and comparison of several susceptibility testing methods against contemporary urine isolates
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- 作者：Elizabeth B. Hirscha ; b ; e.hirsch@neu.edu" class="auth_mail" title="E-mail the corresponding author ; Brian R. Rauxa ; Paola C. Zucchia ; Yisu Kima ; Christopher McCoyb ; James E. Kirbyb ; c ; Sharon B. Wrightb ; c ; George M. Eliopoulosb ; c
- 关键词：UTI ; Uropathogens ; Multidrug-resistant ; Carbapenem-resistant Enterobacteriaceae
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：46
- 期：6
- 页码：642-647
- 全文大小：297 K
文摘
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Fosfomycin susceptibility data from the USA are limited.
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Activity of fosfomycin against 323 clinical urine isolates was determined.
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Overall susceptibility to fosfomycin was 94.4%, 93.5% and 87.9% by agar dilution, disk diffusion and Etest, respectively.
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Fosfomycin displayed fairly consistent activity against a majority of contemporary isolates when using the susceptibility breakpoint of 64 μg/mL.