Joint enhancement strategy applied in ECL biosensor based on closed bipolar electrodes for the detection of PSA
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- 作者：Hai-Wei Shi ; Wei Zhao ; Zhen Liu ; Xi-Cheng Liu ; Mei-Sheng Wu ; Jing-Juan Xu ; xujj@nju.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Hong-Yuan Chen
- 关键词：Electrochemiluminescence ; Bipolar electrode ; Dual-amplification ; PSA detection
- 刊名：Talanta
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：154
- 期：Complete
- 页码：169-174
- 全文大小：1367 K
文摘
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A sensitive ECL approach based on a closed ITO bipolar electrode for PSA detection in human serum was provided.
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A dual-amplification strategy on both poles of closed bipolar electrodes was proposed.
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Th@SiO2 NPs were introduced as both recognition probes for PSA and signal amplification indicators.
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The approach could detect PSA in a wide range from 0.1 pg/mL to 0.1 μg/mL.