Investigating dysregulated pathways in Staphylococcus aureus (SA) exposed macrophages based on pathway interaction network

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• 作者：Wei Zhou^a ; ^b ; Yan Zhang^b ; Yue-Hua Li^b ; Shuang Wang^b ; Jing-Jing Zhang^b ; Cui-Xia Zhang^b ; Zhi-Sheng Zhang^a ; ^{zhishengzhang2016@yeah.net}
• 关键词：Staphylococcus aureus ; Macrophages ; Data dysregulated pathway ; Activity ; Pathway interaction network
• 刊名：Computational Biology and Chemistry
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：66
• 期：Complete
• 页码：21-25
• 全文大小：682 K
• 卷排序：66

文摘

The PIN was comprised of 8388 interactions and 1189 nodes. Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins was the seed pathway. A total of 15 dysregulated pathways were obtained for SA infected samples.