Structural characterization and immunomodulating activity of polysaccharide from Dendrobium officinale
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- 作者：Tao-Bin Hea ; b ; c ; Yan-Ping Huanga ; c ; Liu Yangb ; Ti-Ti Liua ; c ; Wan-Ying Gonga ; c ; Xuan-Jun Wanga ; c ; Jun Shenga ; c ; shengjunpuer@163.com" class="auth_mail" title="E-mail the corresponding author ; Jiang-Miao Hub ; hujiangmiao@mail.kib.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Dendrobium officinale ; Polysaccharide ; Immunomodulation
- 刊名：International Journal of Biological Macromolecules
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：83
- 期：Complete
- 页码：34-41
- 全文大小：1773 K
文摘
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A neutral heteropolysaccharide was purified from dried stem Dendrobium officinale.
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The structure of DOP-1-1 was partially elucidated.
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The antioxidant and immune activities of DOP-1-1 was evaluated.
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DOP-1-1 exhibited significant immune-modulating effect and the immune mechanism of DOP-1-1 was through upregulating NF-кB and ERK1/2.