Noise trauma induced plastic changes in brain regions outside the classical auditory pathway
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- 作者：G.-D. Chen ; gchen7@buffalo.edu" class="auth_mail" title="E-mail the corresponding author ; A. Sheppard ; R. Salvi
- 关键词：ABR ; auditory brainstem response ; AC ; auditory cortex ; CF ; characteristic frequency ; DCN ; dorsal cochlear nucleus ; FRF ; frequency receptive field ; IC ; inferior colliculus ; IHC ; inner hair cells ; LA ; lateral amygdala ; MUC ; multiunit clusters ; NBN ; narrowband noise ; NIHL ; noise-induced hearing loss ; OBN ; octave band noise ; OHC ; outer hair cells ; PTS ; permanent threshold shifts ; Str ; striatum ; SR ; spontaneous discharge rate ; VCN ; ventral cochlear nucleus
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：19 February 2016
- 年：2016
- 卷：315
- 期：Complete
- 页码：228-245
- 全文大小：4551 K
文摘
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High-frequency noise trauma induces hypoactivity at high-frequencies but hyperactivity at low-frequencies.
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A severe injury induces hypoactivity not only at the high-frequencies but also at the edge-frequency.
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A moderate injury induces hypoactivity at the high-frequencies but not at the edge-frequency.
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A minor injury, in contrast, induces hyperactivity at the edge-frequency but not at the low-frequency.
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The noise-induced hyperactivity occurs in the auditory cortex and lateral amygdala but not in striatum.