The solubility of allisartan isoproxil in binary solvent mixtures were determined.
Apelblat, CNIBS/R-K and Jouyban-Acree models were used to correlate the solubility.
Solubility parameter theory was used to explain the co-solvency phenomenon.
Regular mixing rules were used to calculate solubility parameter of binary solvents.
The mixing thermodynamics were calculated and discussed based on NRTL model.