Clinicopathologic implications of DNA mismatch repair status in endometrial carcinomas
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- 作者：Ayumi Shikama ; Takeo Minaguchi ; minaguchit@md.tsukuba.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Koji Matsumoto ; Azusa Akiyama-Abe ; Yuko Nakamura ; Hiroo Michikami ; Sari Nakao ; Manabu Sakurai ; Hiroyuki Ochi ; Mamiko Onuki ; Toyomi Satoh ; Akinori Oki ; Hiroyuki Yoshikawa
- 关键词：Mismatch repair deficiency ; Endometrial carcinoma ; Lynch syndrome ; Survival ; MLH1 promoter methylation
- 刊名：Gynecologic Oncology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：140
- 期：2
- 页码：226-233
- 全文大小：1235 K
文摘
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221 endometrial cancers were classified as sporadic or Lynch syndrome by MMR analyses.
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LS correlated with favorable prognostic factors and sensitivity to adjuvant therapies.
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Analyzing MMR and searching for LS may find patients with favorable survival and sensitivity to adjuvant therapies.