Long-term risks for patency loss in patients with hemodialysis after bare self-expandable nitinol stent implantation to femoropopliteal artery occlusive lesions

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• 作者：Junya Matsumi ; ^{mjunya2318@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Takuma Takada ^{takada0924takuma@icloud.com" class="auth_mail" title="E-mail the corresponding author} ; Noriaki Moriyama ^{e2718nm@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Tomoki Ochiai ^{qqzd72y9k@ever.ocn.ne.jp" class="auth_mail" title="E-mail the corresponding author} ; Kazuki Tobita ^{memento_mori_foram@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Koki Shishido ^{koki10192002@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Kazuya Sugitatsu ^{sugitatsu0706@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Shingo Mizuno ^{radialist-children@song.ocn.ne.jp" class="auth_mail" title="E-mail the corresponding author} ; Futoshi Yamanaka ^{futoshi-yamanaka@nifty.com" class="auth_mail" title="E-mail the corresponding author} ; Masato Murakami ^{murakami20040408@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Yutaka Tanaka ^{yutakatanaka_circ@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Saeko Takahashi ^{saeko@kamakuraheart.org" class="auth_mail" title="E-mail the corresponding author} ; Takeshi Akasaka ^{akasaka-cba@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Shigeru Saito ^{transradial@kamakuraheart.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Long-term results ; Bare-self expandable nitinol stent ; Femoropopliteal ; Patency
• 刊名：International Journal of Cardiology
• 出版年：2016
• 出版时间：15 November 2016
• 年：2016
• 卷：223
• 期：Complete
• 页码：268-275
• 全文大小：1443 K

文摘

Although patients receiving hemodialysis (HD +) have significantly different backgrounds, including a history of progressive atherosclerotic disease, compared with those not receiving hemodialysis (HD −), there are no studies evaluating the risks for loss of primary patency (PP) and need for target lesion revascularization (TLR) in HD + patients following bare self-expandable nitinol stent (BSNS) implantation to femoropopliteal (FP) artery occlusive lesions, after adjusting for differences using propensity score (PS) analysis in observed characteristics between groups.

Methods

We studied 531 limbs of 432 Japanese patients (HD +, n = 107; HD −, n = 325) who received BSNS implantation to FP lesions between 2004 and 2014. Patients were followed-up for an average of 44.3 ± 33.6 months. We compared the long-term results between HD + and HD − patients using the Cox-proportional hazard model with adjustment for inverse probability treatment weight (IPTW) of PS, which was calculated for covariates with HD as a dependent variable.

Results

PP rate in HD + vs. HD − patients at 9 years after the procedure was 19.1% vs. 47.9%, with a freedom from TLR rate of 47.6% vs. 62.9%, respectively. Adjusted HRs in HD + patients with 95% confidence intervals (CIs) were as follows: loss of PP: HR 1.64, 95% CI 1.052–2.557, P = 0.03; TLR: HR 1.862, 95% CI 1.104–3.139, P = 0.02.

Conclusions

The present study suggests that HD + patients have an increased risk for loss of PP and need for TLR after BSNS implantation to FP lesions.