Prognostic value of anemia in predicting sudden death of patients with diastolic heart failure

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• 作者：Tomohiro Tada ; Nobuyuki Shiba ; Jun Watanabe ; Mika Matsuki ; Yutaka Kagaya ; Tsuyoshi Shinozaki ; Kunio Shirato ; Hiroaki Shimokawa
• 刊名：International Journal of Cardiology
• 出版年：2008
• 出版时间：29 August 2008
• 年：2008
• 卷：128
• 期：3
• 页码：419-421
• 全文大小：143 K

文摘

It has been reported that anemia is a prognostic predictor in patients with diastolic heart failure (DHF), however, the relationship between anemia and sudden death in those patients is still unclear. We prospectively studied 357 stable DHF patients and the proportion of anemic patients was 39 % of the study population. During the mean follow-up period of 3.6 ± 1.7 years, 30 (8.4 % ) patients died suddenly. Importantly, the Cox proportional-hazards regression analysis showed that lower hemoglobin level was significantly associated with the development of sudden death in the multivariate model (P < 0.001). Anemia may be an important therapeutic target to reduce sudden death in DHF patients.