A highly efficient and versatile NMR chiral sensor was developed for rapid chiral discrimination and ee determination of a wide range of chiral compounds.
Using a simple one-step synthesized bisthiourea as the NMR chiral sensor can give distinguishable split signals for chiral compounds with a diverse range of structures and functional groups.
The NMR chiral sensing method is rapid, practical and simple to operate, which can be used as a general tool for chiral discrimination and ee determination of various chiral compounds.