A novel data set, GeneNote (<b>Geneb> <b>Nob>rmal <b>Tb>issue <b>Eb>xpression), was produced to portray complete gene expression profiles in healthy human tissues using the Affymetrix GeneChip HG-U95 set, which includes 62839 probe-sets. The hybridization intensities of two replicates were processed and analyzed to yield the complete transcriptome for twelve human tissues. Abundant novel information on tissue specificity provides a baseline for past and future expression studies related to diseases. The data is posted in GeneNote (bject-type=""text/html"">http://genecards.weizmann.ac.il/genenote/"" object-type=""text/html), a widely used compendium of human genes (bioinfo.weizmann.ac.il/genecards"" object-type=""text/html"">http://bioinfo.weizmann.ac.il/genecards"" object-type=""text/html). <b>To cite this article: O. Shmueli et al., C. R. Biologies 326 (2003).b>