Electrochemical deposition of gold nanoparticles on carbon nanotube coated glassy carbon electrode for the improved sensing of tinidazole

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• 作者：Saeed Shahrokhian ; Shokoufeh Rastgar
• 关键词：Gold nanoparticles ; Multi-walled carbon nanotube ; Tinidazole ; Voltammetry
• 刊名：Electrochimica Acta
• 出版年：2012
• 出版时间：1 September, 2012
• 年：2012
• 卷：78
• 期：Complete
• 页码：422-429
• 全文大小：894 K

文摘

The electrochemical reduction of tinidazole (TNZ) is studied on gold-nanoparticle/carbon-nanotubes (AuNP/CNT) modified glassy carbon electrodes using the linear sweep voltammetry. An electrochemical procedure was used for the deposition of gold nanoparticles onto the carbon nanotube film pre-cast on a glassy carbon electrode surface. The resulting nanoparticles were characterized by scanning electron microscopy and cyclic voltammetry. The effect of the electrodeposition conditions, e.g., salt concentration and deposition time on the response of the electrode was studied. Also, the effect of experimental parameters, e.g., potential and time of accumulation, pH of the buffered solutions and the potential sweep rate on the response is examined. Under the optimal conditions, the modified electrode showed a wide linear response toward the concentration of TNZ in the range of 0.1-50 ¦ÌM with a detection limit of 10 nM. The prepared electrode was successfully applied for the determination of TNZ in pharmaceutical and clinical samples.