Comparative study of the efficacy and safety between blonanserin and risperidone for the treatment of schizophrenia in Chinese patients: A double-blind, parallel-group multicenter randomized trial
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- 作者：Huafang Lia ; lhlh_5@163.com" class="auth_mail" title="E-mail the corresponding author ; Chen Yaob ; yaoc301@qq.com" class="auth_mail" title="E-mail the corresponding author ; Jianguo Shic ; sjgysh@sohu.com" class="auth_mail" title="E-mail the corresponding author ; Fude Yangd ; yandf@126.com" class="auth_mail" title="E-mail the corresponding author ; Shuguang Qie ; shuguangqi0208@126.com" class="auth_mail" title="E-mail the corresponding author ; Lili Wangf ; 13920084798@163.com" class="auth_mail" title="E-mail the corresponding author ; Honggeng Zhangg ; gen571@126.com" class="auth_mail" title="E-mail the corresponding author ; Jie Lih ; biglijie@163.com" class="auth_mail" title="E-mail the corresponding author ; Chuanyue Wangi ; w.cy@163.net" class="auth_mail" title="E-mail the corresponding author ; Chuansheng Wangj ; chuansonwang@126.com" class="auth_mail" title="E-mail the corresponding author ; Cui Liuk ; liucui0723@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Lehua Lil ; llyyz2006@126.com" class="auth_mail" title="E-mail the corresponding author ; Qiang Wangm ; wangqiang130@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Keqing Lin ; like1002@sina.com" class="auth_mail" title="E-mail the corresponding author ; Xiaoyan Luoo ; luo@dsmpharm.com.cn" class="auth_mail" title="E-mail the corresponding author ; Niufan Gua ; guniufan@outlook.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antipsychotic agents ; Blonanserin ; Randomized controlled trial ; Risperidone ; Schizophrenia
- 刊名：Journal of Psychiatric Research
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：69
- 期：Complete
- 页码：102-109
- 全文大小：1083 K
文摘
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We compared blonanserin and risperidone for treating Chinese schizophrenia patients.
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Patients aged 18–65 years with a PANSS total score of 70–120 were randomized.
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Based on a PANSS total score change, blonanserin was as effective as risperidone.
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Blonanserin was well tolerated and TEAEs were similar for both groups.
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Blonanserin is a useful novel treatment option for Chinese schizophrenia patients.