Targeting miRNAs associated with surface expression of death receptors to modulate TRAIL resistance in breast cancer
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文摘

Deficient expression of DR4/5 on cell surface involved in resistance to TRAIL in breast cancer.

Regulation of DR4 or DR5 on surface of breast cancer cells.

Role of miRNAs in TRAIL resistant breast cancer cells.

“miRNA-endocytosis/autophagy-cell surface expression of DR4/5” cascades in TRAIL resistance.

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