Impact of process parameters on Mg-St content and tablet surface wettability in the external lubrication method for a rotary tablet press
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- 作者：Takayuki Kamiyaa ; b ; takayuki.kamiya@astellas.com" class="auth_mail" title="E-mail the corresponding author ; Hisami Kondoa ; Hiroyuki Hiromaa ; Kazunari Yamashitaa ; Tadashi Hakomoria ; Kazuhiro Sakoa ; Yasunori Iwaob ; Shuji Noguchib ; Shigeru Itaib
- 关键词：External lubrication ; Tablet lubrication ; Rotary tablet press ; Lubricant concentration ; Magnesium stearate
- 刊名：Advanced Powder Technology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：27
- 期：1
- 页码：193-198
- 全文大小：380 K
文摘
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Tablet wettability by external lubrication was lower than by internal method.
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Tablet wettability can be controlled by the setting of external lubrication system.
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Critical process parameters for Mg–St content were statistically verified.
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Model equation to predict Mg–St content of external lubrication method was shown.