Preparation and characterization of a novel conformed bipolymer paclitaxel-nanoparticle using tea polysaccharides and zein
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- 作者：Shuqin Li lisq2013@sina.com" class="auth_mail" title="E-mail the corresponding author ; Xiuming Wang 610834566@163.com" class="auth_mail" title="E-mail the corresponding author ; Weiwei Li liweiwei0522@163.com" class="auth_mail" title="E-mail the corresponding author ; Guoqi Yuan 13102020187@163.com" class="auth_mail" title="E-mail the corresponding author ; Yuxiang Pan pyx0031@qq.com" class="auth_mail" title="E-mail the corresponding author ; Haixia Chen ; chenhx@tju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tea polysaccharides ; Zein ; Paclitaxel (PTX) ; Nanoparticle ; Characterization
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：1 August 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：52-57
- 全文大小：1821 K
文摘
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A novel conformed bipolymer paclitaxel-nanoparticle using tea polysaccharides and zein was prepared.
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The optimum formula for nanoparticle was obtained using tea polysaccharide as the shell and zein as the core.
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The PTX was encapsulated in an amorphous form and had a typical sustained release.