Accelerated enamel mineralization in Dspp mutant mice
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- 作者：Kostas Verdelisa ; b ; c ; d ; Heather L. Szabo-Rogersa ; b ; e ; Yang Xua ; Rong Chonga ; Ryan Kanga ; Brian J. Cusacka ; Priyam Janif ; Adele L. Boskeyd ; Chunlin Qinf ; Elia Beniasha ; b ; g ; ebeniash@pitt.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Odontogenesis ; Dentin sialophosphoprotein ; Dentin ; Enamel ; Dentino-enamel junction
- 刊名：Matrix Biology
- 出版年：2016
- 出版时间：May-July 2016
- 年：2016
- 卷：52-54
- 期：Complete
- 页码：246-259
- 全文大小：1955 K
文摘
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DSPP is expressed in secretory stage ameloblasts.
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The onset of enamel mineralization occurs earlier and its secretion and maturation are accelerated in Dspp-/-incisors
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Structural organization of the inner enamel layer and the mechanical integrity of the DEJ are compromised in Dspp-/- incisors
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The odontoblast processes were widened and lacked branching near the DEJ in Dspp-/- incisors