Transgenic expression of Dspp lengthened the long bone of Dmp1-null mice.
Dspp transgenic expression improved the cortical bone of Dmp1-null mice.
Dspp overexpression improved the collagen network of Dmp1-deficient bone.
Overexpressing Dspp improved the lacunocanalicular system of Dmp1-deficient bone.
Transgenic Dspp corrected the altered levels of ECM molecules in Dmp1-deficient bone.