Sialyltransferase inhibition and recent advances
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- 作者：Libo Wanga ; wanglibo66@sina.com" class="auth_mail" title="E-mail the corresponding author ; Ying Liua ; Lijun Wua ; Xue-Long Sunb ; x.sun55@csuohio.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sialic acids ; Sialylation ; Sialyltransferases ; Polysialyltransferases ; CMP-sialic acid ; Fluorinated sialic acid
- 刊名：Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：1864
- 期：1
- 页码：143-153
- 全文大小：4638 K
文摘
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105">Overexpression of cell surface sialic acids contributes to disease developments.
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110">Sialyltransferases contribute to hypersialylation and thus are potential drug targets.
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115">Inhibitors of sialyltransferases are of medicinal interest, especially for the cancer therapy.