On MRI turbulence quantification

详细信息    查看全文

• 作者：Petter Dyverfeldt ; Rol ; Gå ; rdhagen ; Andreas Sigfridsson ; Matts Karlsson ; Tino Ebbers
• 关键词：Turbulence quantification ; Turbulent flow ; Phase-contrast magnetic resonance imaging ; Constriction ; Numerical flow phantom
• 刊名：Magnetic Resonance Imaging
• 出版年：2009
• 出版时间：September 2009
• 年：2009
• 卷：27
• 期：7
• 页码：913-922
• 全文大小：625 K

文摘

Turbulent flow, characterized by velocity fluctuations, accompanies many forms of cardiovascular disease and may contribute to their progression and hemodynamic consequences. Several studies have investigated the effects of turbulence on the magnetic resonance imaging (MRI) signal. Quantitative MRI turbulence measurements have recently been shown to have great potential for application both in human cardiovascular flow and in engineering flow. In this article, potential pitfalls and sources of error in MRI turbulence measurements are theoretically and numerically investigated. Data acquisition strategies suitable for turbulence quantification are outlined. The results show that the sensitivity of MRI turbulence measurements to intravoxel mean velocity variations is negligible, but that noise may degrade the estimates if the turbulence encoding parameter is set improperly. Different approaches for utilizing a given amount of scan time were shown to influence the dynamic range and the uncertainty in the turbulence estimates due to noise. The findings reported in this work may be valuable for both in vitro and in vivo studies employing MRI methods for turbulence quantification.