- 作者：Germá ; n Latorre Gonzá ; lez ; ger.latorre@gmail.com ; Ana Belé ; n Escribano Gascó ; n ; Carlos Ló ; pez de Silanes de Miguel ; Rocí ; o Garcí ; a Cobos ; Luis Ignacio Casanova Peñ ; o ; Teresa Lapeñ ; a Montero
- 关键词：Enfermedad de Behç ; et ; Neurobehç ; et ; Afectació ; n neuroló ; gica
- 刊名：Reumatolog¨ªa Cl¨ªnica
- 出版年：2009
- 出版时间：July-August 2009
- 年：2009
- 卷：5
- 期：4
- 页码：168-170
- 全文大小：177 K
Beh?et¡äs disease is an inflammatory systemic disorder, with oral and genital ulcers, as well as ophthalmologic and cutaneous disturbances. 5 % of the patients have neurological alterations. We present a case of neuroBeh?et with a rare neurological involvement.
A 28 years-old male patient with recurrent oral and genital ulcer history and folliculitis presents 48 h progressive fever, headache, nausea, right sixth cranial nerve palsy and right upper limb paresis. The CSF showed lymphocyte pleocytosis and high proteinorrachia, so antibiotic treatment was initiated. Cerebral MR found hyperintense enhancing lesions in the brainstem and left transverse sinus thrombosis. Patient improved with endovenous corticosteroids and was discharged asymptomatic.
Neurological involvement in Beh?et¡äs disease is rare and moreover the coexistence of parenchymatous and non-parenchymatous alterations in the same patient. It normally has a good response to immunosuppressant treatment.