Human malignant mesothelioma: Molecular mechanisms of pathogenesis and progression

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• 作者：Enrico P. Spugnini ; Silvano Bosari ; Gennaro Citro ; Italo Lorenzon ; Francesco Cognetti and Alfonso Baldi
• 关键词：Mesothelioma ; Molecular markers ; Pathogenesis ; Progression ; Therapy
• 刊名：The International Journal of Biochemistry and Cell Biology
• 出版年：2006
• 出版时间：2006
• 年：2006
• 卷：38
• 期：12
• 页码：2000-2004
• 全文大小：167 K

文摘

The continuing identification and elucidation of the molecular defects involved in mesothelioma pathogenesis and progression should lead to better disease control and greater therapeutic options in the near future. Goal of this review article is to summarize the most recent advances in molecular pathogenesis of mesothelioma and discuss possible therapeutic implications of these findings.