The anti-inflammatory effect of Ilex paraguariensis A. St. Hil (Mate) in a murine model of pleurisy
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- 作者：Ana Beatriz Gobbo Luza ; anaaabia@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Carlos Henrique Blum da Silvab ; carloshblum@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Marcus Vinicius P.S. Nascimentoa ; mmmarcusster@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Bruno Matheus de Campos Facchina ; brunomatheusfacchin@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Bruna Barattoa ; bruhb90@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Tâ ; nia Silvia Frö ; dea ; tania.frode@ufsc.br" class="auth_mail" title="E-mail the corresponding author ; Flá ; vio Henrique Reginattob ; flavio.reginatto@ufsc.br" class="auth_mail" title="E-mail the corresponding author ; Eduardo Monguilhott Dalmarcoa ; c ; eduardo.dalmarco@ufsc.br" class="auth_mail" title="E-mail the corresponding author ; edalmarco@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ilex paraguariensis ; Carrageenan ; Pleurisy ; Th1/Th17 polarization ; Anti-inflammatory
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：36
- 期：Complete
- 页码：165-172
- 全文大小：455 K
文摘
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Ilex paraguariensis shows an important immunomodulatory and anti-inflammatory profile.
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Anti-inflammatory mechanism of action occurs through the immunomodulatory pathway.
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Ilex paraguariensis attenuates Th1/Th17 polarization.
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Suppression of pro-inflammatory cytokine production was due to NF-κB inhibition.
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The use mate as a beverage can be a factor against Th1/Th17 inflammatory diseases.