Should Gynecologic Maturity Change the Management of Cervical Cytologic Atypia During Adolescence?

详细信息    查看全文

• 作者：Kelly ; Lisa ; Bleistein ; Abbey ; Stevens-Simon ; Catherine
• 关键词：Cervical cancer ; Colposcopy ; Human papilloma virus ; Squamous intraepithelial lesions
• 刊名：Journal of Pediatric and Adolescent Gynecology
• 出版年：1999
• 出版时间：1999
• 年：1999
• 卷：12
• 期：4
• 页码：203-207
• 全文大小：366 K

文摘

Study Objective: To test the hypothesis that atypical cytology (ASCUS) portends ominous histologic diagnoses during adolescence.

Methods: The prevalence of squamous intraepithelial lesions (SILs) was determined in a racially diverse group of thirty-six 14- to 21-year-olds who were undergoing colposcopy evaluation of ASCUS cytology. The prevalence of 10 widely accepted risk factors for SIL was also qualified.

Results: SILs were detected in biopsies obtained from 20 (56 % ) of the 36 study subjects. There were 15 (39 % ) low-grade SILs and 5 (17 % ) high-grade SILs. No single risk factor or combination of risk factors distinguished subjects with SIL histology from those with more benign diagnoses.

Conclusion: The hypothesis was supported. More than half (56 % ) of the adolescents we studied with ASCUS cytology had SIL histology. The findings suggest that immediate colposcopy evaluation may be prudent for adolescents with ASCUS cytology that cannot be attributed to concurrent lower genital tract infections.