Detecting Alzheimer's disease biomarkers: From antibodies to new bio-mimetic receptors and their application to established and emerging bioanalytical platforms - A critical review
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- 作者：Simona ScaranoaAuthor Vitae ; Samuele Lisia ; bAuthor Vitae ; Corinne RaveletbAuthor Vitae ; Eric PeyrinbAuthor Vitae ; Maria Minunnia ; maria.minunni@unifi.it" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Alzheimer's disease ; Diagnosis ; Biomarkers ; Biosensors ; Amyloid beta ; Tau protein
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：12 October 2016
- 年：2016
- 卷：940
- 期：Complete
- 页码：21-37
- 全文大小：2019 K
文摘
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Alzheimer's biomarkers detection on conventional and innovative platforms are reviewed.
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Analytical performances in detecting amyloid-β and Tau protein species are reported.
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Critical aspects related to inter-laboratory variability of results are discussed.
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Emerging synthetic receptors for AD biomarkers detection are presented and compared.
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Future outlooks on alternative matrices and AD biomarkers are presented.