Giardia duodenalis GlSir2.2, homolog of SIRT1, is a nuclear-located and NAD+-dependent deacethylase
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- 作者：Yun-Hua Wanga ; c ; yunhua1977@126.com" class="auth_mail" title="E-mail the corresponding author ; Guo-Xia Zhengb ; c ; Ya-Jie Lia ; c
- 关键词：Giardia duodenalis ; Silent information regulator proteins ; Nicotinamide adenine dinucleotide ; Deacetylase
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：169
- 期：Complete
- 页码：28-33
- 全文大小：2046 K
文摘
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Giardia encodes unique sir2 family protein, GlSIR2.2, which was homolog of SIRT1.
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GlSIR2.2 GlSIR2.2 is a nuclear-located, NAD+-dependent deacetylase.
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GlSIR2.2 could be inhibited by nicotinamide, but not by splitomicin and sirtinol.