- 作者：Rinoza BafiqAuthor Vitae ; Raeba Mathew ; Elizabeth Pearce ; Ahmed Abdel-Hey ; Matthew Richardson ; Thomas Bailey ; Sobha Sivaprasad ; senswathi@aol.com" class="auth_mail" title="E-mail the corresponding author
- 刊名：American Journal of Ophthalmology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：160
- 期：5
- 页码：1034-1043.e1
- 全文大小：962 K
Design
Single-center observational cross-sectional study.
Methods
Ninety randomly selected, healthy individuals of white, black, and South Asian origin underwent SD OCT raster and enhanced depth imaging scan. Manual measurements of inner and outer retinal thickness and choroidal thickness up to 3 mm nasal and temporal to the fovea were performed. The age, sex, and ethnic differences in these parameters were analyzed.
Results
The mean inner retinal thickness was lower by approximately 12 渭m in black subjects across the central retina compared to white subjects (P < .05). The central foveal thickness below the foveal pit was lower in eyes of blacks compared to South Asians (12 渭m, P = .035) and white subjects (18 渭m, P < .0001). The fovea was also significantly wider in eyes of black and South Asian subjects compared to white individuals. The inner retinal thickness decreased by 0.5 渭m per year of age of subjects and was thinner by 6.1 渭m (P < .02) in female compared to male subjects. The subfoveal choroidal thickness did not vary between ethnic groups but the temporal choroid was significantly thinner in black subjects (P < .05). The choroid showed an age-related decline in thickness of 2 渭m per year of age of the subjects.
Conclusions
Interethnic differences include wider fovea, lower central foveal thickness, and thinner inner retina in eyes of black subjects compared to their white and South Asian counterparts.