The CDH cases were abstracted from a disease-specific, 16-hospital, national network. Thirteen hospitals participated in this study. Anonymized hospitals were categorized as either high (>6 cases) or low-volume (≤6 cases) centers (HVC, n = 6; LVC, n = 7) according to the median case number per center. Risk-adjusted (Score for Neonatal Acute Physiology, version II [SNAP-II] score) mortality rates were compared between HVC and LVC.
One hundred twenty-one CDH cases were identified. Overall in-hospital survival was 81 % . No significant difference in SNAP-II score was observed between HVC and LVC. Of 97 (15 % ) infants treated in 6 HVC, 15 (15 % ) died compared to 8 (33 % ) of 24 in 7 LVC (P < .05).
Hospital case volume may be partially responsible for mortality rate variation in CDH. This result requires careful analysis, as case volume may merely be a surrogate for other predictive variables.