Protein hot spots at bio-nano interfaces

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• 作者：Gerald F. Audette ; Stephanie Lombardo ; Jonathan Dudzik ; Thomas M. Arruda ; Michal Kolinski ; Slawomir Filipek ; Sanjeev Mukerjee ; Arunachala Mada Kannan ; Velmurugan Thavasi ; Seeram Ramakrishna ; Michael Chin ; Ponisseril Somasundaran ; Sowmya Viswanathan ; Resat S. Keles ; Venkatesan Renugopalakrishnan
• 刊名：Materials Today
• 出版年：2011
• 出版时间：July-August 2011
• 年：2011
• 卷：14
• 期：7-8
• 页码：360-365
• 全文大小：924 K

文摘

Nanotechnology has influenced the direction of research across the sciences, medicine, and engineering. Carbon nanotubes (CNTs) and, more recently, protein nanotubes (PNTs) and protein-inorganic nanocomposites have received considerable attention due to their unique nanostructures that can be utilized as a scaffold to house proteins or create nanowires. A shift towards protein-inorganic interactions has numerous applications from biosensors to biofuel cells and bio-based nanodevices. We examine several systems where protein hot spots, the active domains on proteins and the interactive dynamics in them, play a critical role in the interactions at the interface of these unique systems.