Dendritic cells in liver injury and fibrosis: Shortcomings and promises

详细信息    查看全文

• 作者：Veronika Lukacs-Kornek ; Detlef Schuppan
• 关键词：APC ; antigen presenting cell ; BM ; bone marrow ; BDL ; bile duct ligation ; DCs ; dendritic cells ; Batf3 ; basic leucine zipper transcription factor ; ATF-like 3 ; CCL4 ; carbon tetrachloride ; CTL ; cytotoxic T lymphocyte ; DT ; diphtheria toxin ; DTR ; diphtheria toxi
• 刊名：Journal of Hepatology
• 出版年：2013
• 出版时间：November, 2013
• 年：2013
• 卷：59
• 期：5
• 页码：1124-1126
• 全文大小：391 K

文摘

| Figures/TablesFigures/Tables | ReferencesReferences

Summary

The phenotype and function of liver dendritic cells (LDCs) are poorly understood. This Snapshot summarizes our current knowledge on LDCs in the healthy and injured liver, and their role in fibrosis progression and reversal. It also draws attention to various pitfalls in the current experimental design and conclusions based on available data.