Neurotoxins from Clostridium botulinum (serotype A) isolated from the soil of Mendoza (Argentina) differ from the A-Hall archetype and from that causing infant botulism
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- 作者：P. Caballeroa ; 1 ; M. Troncosob ; 1 ; S.I. Pattersonb ; C. Ló ; pez Gó ; meza ; R. Fernandeza ; M.A. Sosab ; msosaescudero@yahoo.com.ar" class="auth_mail" title="E-mail the corresponding author
- 关键词：Botulism ; Neurotoxins ; Clostridium botulinum ; Infant botulism ; SNAREs
- 刊名：Toxicon
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：30-35
- 全文大小：1027 K
文摘
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Native strains of Clostridium botulinum were isolated from soil or infant botulism feces and studied comparatively.
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The neurotoxins purified from these strains are similar at molecular level but different than that of A-Hall strain.
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The neurotoxin from soil Clostridium botulinum showed to be more potent than that from infant botulism.
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The neurotoxins from both strains can cleave SNARE proteins differentially.