Expression and subcellular localization of the Qa-SNARE syntaxin17 in human eosinophils
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- 作者：Lí ; via A.S. Carmoa ; 1 ; Felipe F. Diasa ; 1 ; Ká ; ssia K. Maltaa ; Ká ; tia B. Amarala ; Revital Shamrib ; Peter F. Wellerb ; Rossana C.N. Meloa ; b ; rossana.melo@ufjf.edu.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：SNARES ; Syntaxin17 ; Human eosinophils ; Transmission electron microscopy ; Immunogold electron microscopy ; Secretory granules ; Eosinophil sombrero vesicles ; Vesicular trafficking
- 刊名：Experimental Cell Research
- 出版年：2015
- 出版时间：1 October 2015
- 年：2015
- 卷：337
- 期：2
- 页码：129-135
- 全文大小：2752 K
文摘
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First demonstration of the Qa-SNARE syntaxin-17 (STX17) in human eosinophils.
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High resolution immunogold EM shows STX17 in granules and tubular vesicles.
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Unstimulated, TNF-伪 or CCL11-stimulated eosinophils express STX17.
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Our findings suggest a role for STX17 in the transport of granule-derived cargos.