d="p0005">A large variation of amino acid changes over time was observed for all subjects.
dd><dt class="label">•dt><dd>d="p0010">NS5A drug resistant variant D320E, detected in vitro, was found in two subjects.
dd><dt class="label">•dt><dd>d="p0015">A low number of positions under positive selective pressure was detected.
dd><dt class="label">•dt><dd>d="p0020">Power to assess links of alisporivir/interferon with amino acid changes was limited.
dd>dl>