Steroid-Responsive Encephalopathy, Dropped Head Syndrome, and Hypertension in a Toddler: Is There a Clue?

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• 作者：Arushi Gahlot Saini ; MD ; DM (Pediatric Neurology)^a ; Jitendra Kumar Sahu ; MD ; DM (Pediatric Neurology)^a ; Saptharishi Lalgudi Ganeshan ; MD ; DM (Pediatric Critical Care)^a ; Kushaljit Singh Sodhi ; MD (Radiodiagnosis)^b ; Katragadda Laxmi Narayan Rao ; MS ; FACS ; FAMS ; FICS^c ; Pratibha Singhi ; MD (Pediatrics) ; FIAP ; FNAMS^a ; ^{doctorpratibhasinghi@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：neuroblastoma ; encephalopathy ; dropped head syndrome ; paraneoplastic ; cardiomyopathy
• 刊名：Pediatric Neurology
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：57
• 期：Complete
• 页码：95-97
• 全文大小：489 K

文摘

Paraneoplastic manifestations may provide an early clue to underlying malignancies in children.

Methods

ra0015">We describe a 3-year-old girl with an unusual neurological paraneoplastic syndrome of steroid-responsive encephalopathy and dropped head syndrome associated with paraspinal neuroblastoma.

Results

ra0020">Cranial neuroimaging, metabolic screen, and thyroid functions were normal. Abdominal imaging identified a paraspinal neuroblastoma. Encephalopathy and neck extensor weakness responded to pulse corticosteroids followed by tumor resection.

Conclusions

ra0025">This is a unique child with paraneoplastic steroid-responsive encephalopathy and dropped head syndrome in association with neuroblastoma.