Human soleus sarcomere lengths measured using in vivo microendoscopy at two ankle flexion angles

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• 作者：Xuefeng Chen^a ; Scott L. Delp^a ; ^b ; ^{delp@stanford.edu}
• 关键词：Muscle ; Sarcomere ; Soleus ; Ankle ; In vivo imaging
• 刊名：Journal of Biomechanics
• 出版年：2016
• 出版时间：8 December 2016
• 年：2016
• 卷：49
• 期：16
• 页码：4164-4167
• 全文大小：466 K
• 卷排序：49

文摘

The forces generated by the soleus muscle play an important role in standing and locomotion. The lengths of the sarcomeres of the soleus affect its force-generating capacity, yet it is unknown how sarcomere lengths in the soleus change as a function of ankle flexion angle. In this study, we used microendoscopy to measure resting sarcomere lengths at 10° plantarflexion and 20° dorsiflexion in 7 healthy individuals. Mean sarcomere lengths at 10° plantarflexion were 2.84±0.09 µm (mean±S.E.M.), near the optimal length for sarcomere force generation. Sarcomere lengths were 3.43±0.09 µm at 20° dorsiflexion, indicating that they were longer than optimal length when the ankle was in dorsiflexion and the muscle was inactive. Our results indicate a smaller sarcomere length difference between two ankle flexion angles compared to estimates from musculoskeletal models and suggest why these models frequently underestimate the force-generating capacity of the soleus.