New binary and ternary platinum(II) formamidine complexes: Synthesis, characterization, structural studies and in-vitro antitumor activity
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- 作者：Ahmed A. Solimana ; b ; ahmedsoliman61@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Othman I. Alajrawya ; c ; Fawzy A. Attabya ; W. Linertd
- 关键词：Pt(II) complexes ; Ternary complexes ; Formamidine ; Cytotoxicity ; DFT calculations
- 刊名：Journal of Molecular Structure
- 出版年：2016
- 出版时间：5 July 2016
- 年：2016
- 卷：1115
- 期：Complete
- 页码：17-32
- 全文大小：2596 K
文摘
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Binary and ternary Pt(II) complexes were synthesized and characterized.
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The structures are geometrically optimized and the computed vibrations and transition are compared with the experimental.
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The energies of the HOMO and LUMO orbitals of the complexes were computed and interpreted.
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The cytotoxicity of some complexes was tested with promising IC50 values.