Cone beam CT for organs motion evaluation in pediatric abdominal neuroblastoma

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• 作者：Mohamed Soliman Nazmy ; ^{mnazmy@hotmail.com} ; Yasser Khafaga ; Amr Mousa ; Ehab Khalil
• 关键词：CBCT ; Neuroblastoma ; IGRT ; Organ motion
• 刊名：Radiotherapy and Oncology
• 出版年：2012
• 出版时间：March, 2012
• 年：2012
• 卷：102
• 期：3
• 页码：388-392
• 全文大小：534 K

文摘

Background and purpose

To quantify the organ motion relative to bone in different breathing states in pediatric neuroblastoma using cone beam CT (CBCT) for better definition of the planning margins during abdominal IMRT.

Methods and materials

Forty-two datasets of kV CBCT for 9 pediatric patients with abdominal neuroblastoma treated with IMRT were evaluated. Organs positions on planning CT scan were considered the reference position against which organs and target motions were evaluated. The position of the kidneys and the liver was assessed in all scans. The target movement was evaluated in four patients who were treated for gross residual disease.

Results

The mean age of the patients was 4.1 ¡À 1.6 years. The range of target movement in the craniocaudal direction (CC) was 5 mm. In the CC direction, the range of movement was 10 mm for the right kidney, and 8 mm for the left kidney. Similarly, the liver upper edge range of motion was 11 mm while the lower edge range of motion was 13 mm.

Conclusions

With the use of daily CBCT we may be able to reduce the PTV margin. If CBCT is not used daily, a wider margin is needed.