Response assessment after stereotactic body radiotherapy for spinal metastasis: a report from the SPIne response assessment in Neuro-Oncology (SPINO) group

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• 作者：Isabelle Thibault ; MD^a ; Prof Eric L Chang ; MD^b ; Prof Jason Sheehan ; MD^c ; Manmeet S Ahluwalia ; MD^d ; Prof Matthias Guckenberger ; MD^g ; ^h ; Moon-Jun Sohn ; MDⁱ ; Prof Samuel Ryu ; MD^j ; Matthew Foote ; MBBS^k ; Prof Simon S Lo ; MB ChB^l ; Prof Alexander Muacevic ; MD^m ; Scott G Soltys ; MDⁿ ; Samuel Chao ; MD^e ; Prof Peter Gerszten ; MD^o ; Eric Lis ; MD^p ; Eugene Yu ; MD^r ; Prof Mark Bilsky ; MD^q ; Prof Charles Fisher ; MD^s ; Prof David Schiff ; MD^t ; Prof Michael G Fehlings ; MD^u ; Prof Lijun Ma ; PhD^v ; Prof Susan Chang ; MD^w ; Prof Edward Chow ; MBBS^x ; Wendy R Parelukar ; MD^y ; Prof Michael A Vogelbaum ; MD^f ; Dr Arjun Sahgal ; MD^x ; ^{arjun.sahgal@sunnybrook.ca" class="auth_mail" title="E-mail the corresponding author}
• 刊名：The Lancet Oncology
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：16
• 期：16
• 页码：e595-e603
• 全文大小：1151 K

文摘

The SPine response assessment In Neuro-Oncology (SPINO) group is a committee of the Response Assessment in Neuro-Oncology working group and comprises a panel of international experts in spine stereotactic body radiotherapy (SBRT). Here, we present the group's first report on the challenges in standardising imaging-based assessment of local control and pain for spinal metastases. We review current imaging modalities used in SBRT treatment planning and tumour assessment and review the criteria for pain and local control in registered clinical trials specific to spine SBRT. We summarise the results of an international survey of the panel to establish the range of current practices in assessing tumour response to spine SBRT. The ultimate goal of the SPINO group is to report consensus criteria for tumour imaging, clinical assessment, and symptom-based response criteria to help standardise future clinical trials.