New heterogenized C

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• 作者：Norma A. Cortez ; Gerardo Aguirre ; Miguel Parra-Hake ; Ratnasamy Somanathan
• 关键词：Asymmetric transfer hydrogenation ; Sulfonamide ligands ; Rh(III) complex ; Heterogenized ligands
• 刊名：Tetrahedron Letters
• 出版年：2009
• 出版时间：13 May 2009
• 年：2009
• 卷：50
• 期：19
• 页码：2228-2231
• 全文大小：560 K

文摘

C₂-symmetric bis(sulfonamide) ligands derived from chiral trans-(1R,2R)-cyclohexane-1,2-diamine were immobilized on silica gel and on polystyrene resin, and complexed to Rh^IIICp*. The resulting complexes were used as catalysts in the asymmetric transfer hydrogenation (ATH) of acetophenone. The chiral secondary alcohol was obtained in high yields (>99 % ) and enantioselectivities (92 % ) with aqueous sodium formate as the hydride source. The immobilized catalysts were recycled with no loss in activity.