Laser-evoked cortical responses in freely-moving rats reflect the activation of C-fibre afferent pathways
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- 作者：X.L. Xiaa ; c ; 1 ; W.W. Penga ; c ; 1 ; G.D. Iannettib ; 2 ; L. Hua ; b ; c ; 2 ; hulitju@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：LEPs ; laser-evoked potentials ; ECoG ; electrocorticography ; LMM ; linear mixed modeling ; FDR ; false discovery rate ; S1 ; primary somatosensory cortex ; S1FL ; the forelimb areas in the S1 ; S1HL ; the hindlimb areas in the S1 ; S2 ; secondary somatosensory cortex ; ACC ; anterior cingulate cortex
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：128
- 期：Complete
- 页码：209-217
- 全文大小：2233 K
文摘
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We describe the physiological properties of LEPs in freely-moving rats, using ECoG.
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Rat LEPs reflect the activation of C-fibre afferent pathways.
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LEP amplitude reflects stimulus energy and rat nocifensive behavior.
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Similar to their human counterpart, rat LEPs consist of three distinct deflections.
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LEPs in freely-moving rats are a valid model for translational pain research.