Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1-Ras dependent pathway
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- 作者：Nathanael J. Leea ; 1 ; Jung Min Songa ; 1 ; Hyun-Ji Chod ; 1 ; You Me Sunga ; b ; 1 ; Taehee Leea ; Andrew Chunga ; Sung-Ha Honga ; b ; Jessica L. Cifellie ; Mark Rubinshteine ; Lila K. Habibf ; Christina C. Capulee ; R. Scott Turnerb ; Daniel T.S. Pakc ; Jerry Yange ; Hyang-Sook Hoea ; b ; d ; sookhoe72@kbri.re.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：BTA-EG6 ; Dendritic spine ; Ras signaling ; Rap signaling
- 刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：1862
- 期：2
- 页码：284-295
- 全文大小：4617 K
文摘
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BTA-EG6 increases dendritic spine number in vitro.
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BTA-EG6 increases the number of excitatory synapse.
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BTA-EG6 increases the cell surface levels of GluA1 and GluA2.
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BTA-EG6 increases spinogenesis through Ras, but not Rap signaling pathway.