The discovery of structural and functional similarities between the product of the nematode cell-death gene
and mammalian interleukin-1β-converting enzyme (ICE) is providing important insights into the molecular mechanism of apoptosis. This article summarizes the current knowledge of ICE and its homologues, and how these may be involved in regulating apoptosis.
Cited by: | - Diao, Jingyu; Garces, Robert; Richardson, Christopher D.,""X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis""Cytokine and Growth Factor Reviews2001pp. 189-205
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