Is bone equally responsive to calcium and vitamin D intake from food vs. supplements? Use of ⁴¹calcium tracer kinetic model

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• 作者：Tara S. Rogers^a ; Marjorie G. Garrod^b ; Janet M. Peerson^a ; Darren J. Hillegonds^c ; Bruce A. Buchholz^c ; Elieke Demmer^a ; Christine Richardson^a ; Erik R. Gertz^b ; Marta D. Van Loan^a ; ^b ; ^{marta.vanloan@ars.usda.gov}
• 关键词：AI ; adequate intake ; AMS ; accelerator mass spectrometry ; ANOVA ; analysis of variance ; BAP ; bone specific alkaline phosphatase ; BMC ; bone mineral content ; BMD ; bone mineral density ; BMI ; body mass index ; 41Ca ; calcium-41 ; CTx ; serum C terminal telopeptide of type 1 collagen ; CV ; coefficient of variation ; DXA ; dual energy X-ray absorptiometry ; ELISA ; enzyme linked immune-sorbent assay ; HCl ; hydrochloric acid ; nCi ; nanocurrie ; NH4OH ; ammonium hydroxide ; NDSR ; Nutrition Data System for Research ; qCT
• 刊名：Bone Reports
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：5
• 期：Complete
• 页码：117-123
• 全文大小：622 K
• 卷排序：5

文摘

Investigated, using 41Ca tracer, whether bone response to calcium and vitamin D differed based on the source of nutrients, foods vs. supplements. There was no difference in the bone response by treatment group. Both dairy foods and supplements resulted in reduce 41Ca excretion in urine. Reduction in 41Ca excretion occurred with 2 weeks of initiating the interventions. Removal of interventions resulted in 41Ca excretion returning to pre-intervention levels