The impact of IL10 polymorphisms and sHLA-G levels on the risk of schizophrenia
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- 作者：Ashwini Rajasekarana ; b ; Venkataram Shivakumarb ; c ; Sunil V. Kalmadyb ; c ; Janardhanan C. Narayanaswamyb ; c ; Manjula Subbanaa ; b ; Deepthi Venugopala ; b ; Anekal C. Amareshab ; Ganesan Venkatasubramanianb ; c ; Monojit Debnatha ; monozeet@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：MIA ; maternal immune activation ; IL ; interleukin ; HLA-G ; human leukocyte antigen-G ; DSM ; diagnostic and statistical manual of mental disorders ; SAPS ; scale for the assessment of positive symptoms ; SANS ; scale for the assessment of negative symptoms ; MINI ; mini international neuropsychiatric interview ; sHLA-G ; soluble human leukocyte antigen G ; PCR-RFLP ; polymerase chain reaction-restriction fragment length polymorphism ; ELISA ; enzyme linked immuno-sorbent assay ; 4-PL ; 4-parameter logistic ; CV ; c
- 刊名：Asian Journal of Psychiatry
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：23
- 期：Complete
- 页码：39-43
- 全文大小：485 K
文摘
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Roles of IL-10 and HLA-G were evaluated in schizophrenia patients.
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IL-10 gene does not confer risk to schizophrenia.
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CC genotype of IL10 −592C > A polymorphism correlates to lower sHLA-G levels in schizophrenia.