Bioengineered cell culture systems of central nervous system injury and disease
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- 作者：Fá ; bio G. Teixeira1 ; 2 ; Natá ; lia L. Vasconcelos1 ; 2 ; Eduardo D. Gomes1 ; 2 ; Fernanda Marques1 ; 2 ; Joã ; o C. Sousa1 ; 2 ; Nuno Sousa1 ; 2 ; Nuno A. Silva1 ; 2 ; Rita Assunç ; ã ; o-Silva1 ; 2 ; Rui Lima1 ; 2 ; Antó ; nio J. Salgado1 ; 2 ; asalgado@ecsaude.uminho.pt" class="auth_mail" title="E-mail the corresponding author
- 刊名：Drug Discovery Today
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：21
- 期：9
- 页码：1456-1463
- 全文大小：880 K
文摘
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3D cell culture models are needed in as current 2D models do not recapitulate the CNS niche.
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Combinatory strategies using cells, hydrogels and microfluidics chambers allow to develop 3D cell culture models.
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The development of 3D cell culture models will provide the tools for future models that recapitulate the degenerative or injured CNS.