Performance of Photon-Counting Breast Computed Tomography, Digital Mammography, and Digital Breast Tomosynthesis in Evaluating Breast Specimens

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• 作者：Ann-Christin Rö ; ß ; ler^a ; ^{ann-christin.roessler@imp.uni-erlangen.de} ; Willi Kalender^a ; ^b ; Daniel Kolditz^a ; ^b ; Christian Steiding^a ; ^b ; ^c ; Veikko Ruth^a ; Caroline Preuss^d ; Sandra Christina Peter^c ; Barbara Brehm^c ; Matthias Hammon^c ; Rü ; diger Schulz-Wendtland^c ; Evelyn Wenkel^c
• 关键词：Breast computed tomography ; digital mammography ; digital breast tomosynthesis ; photon-counting detector ; specimen
• 刊名：Academic Radiology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：24
• 期：2
• 页码：184-190
• 全文大小：1531 K
• 卷排序：24

文摘

This study compared a novel photon-counting breast computed tomography (pcBCT) system with digital mammography (DM) and digital breast tomosynthesis (DBT) systems. For this reason, surgical specimens were examined with all three techniques and rated by three observers.Materials and MethodsA total of 30 surgical specimens were investigated with DM, DBT, and pcBCT; the associated images were shown to three experienced radiologists. Findings (22 microcalcifications and 23 mass lesions) were recorded and compared to the results of the pathological examination. Sensitivity and specificity for detection of microcalcifications and lesions were calculated and displayed using receiver operating characteristic curves.ResultsSensitivity for microcalcifications was 82% for DM, 70% for DBT, and 85% for pcBCT. Specificity for microcalcifications was 71% for DM, 75% for DBT, and 83% for pcBCT. Sensitivity for lesions was 45% for DM, 62% for DBT, and 65% for pcBCT. Specificity for lesions was 76% for DM, 62% for DBT, and 76% for pcBCT.ConclusionspcBCT showed a comparable or superior performance compared to the clinically approved DM and DBT systems. Mass lesion detectability can be increased further by the use of contrast media.